Showing posts with label CPOE. Show all posts
Showing posts with label CPOE. Show all posts

Wednesday, February 11, 2009

Clinicians Ignore most eRx Alerts

What in medicine do we tolerance 90%+ false positive rates, without getting rid of it?
We have a long way to go in CDS.  Below is from a ASHP press release on a new Archives of IM study, recommended read.
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Clinicians Ignore Most e-Prescribing Alerts
Kate Traynor

BETHESDA, MD 09 February 2009—A large study of electronic prescribing in the outpatient setting suggests that prescribers override most warnings that indicate a medication allergy or drug interaction, according to a report in the February 9 Archives of Internal Medicine.

The analysis of data for 2872 prescribers in Massachusetts, New Jersey, and Pennsylvania over a nine-month period in 2006 found that the clinicians accepted 23% of alerts for medication allergies and 9.2% of drug interaction alerts. Alerts were almost always ignored for medications that had been previously prescribed for the patient.

The study examined more than 3 million electronic prescriptions generated using Zix Corporation's PocketScript program. Of these, about 6.6% resulted in an interaction alert to the prescriber. Less than 2% of the alerts were for medication allergies; the rest informed the clinician that the selected medication potentially interacts with another drug currently taken by the patient.

Drug interactions were classified in the prescribing program as low, medium, or high severity, and the severity level was displayed on the prescribing device's screen. About 62% of the alerts in the study were classified as high severity, and 29% were of medium severity. High-severity alerts were overridden about 90% of the time, and lower-level alerts were disregarded about 93% of the time.

According to the report, PocketScript's severity classifications are produced by pharmacists at a health information technology company. The report's authors suggested that reexamining and reclassifying some of the high-severity alerts, particularly those that are most often overridden, may increase prescribers' acceptance of drug-interaction warnings.

Prescribers took some high-severity drug–drug interactions more seriously than others. For example, warnings not to use noncardioselective beta-blockers and macrolides together were accepted 43.1% of the time.

The next-most-commonl...

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Monday, December 29, 2008

Top articles of 2008

The envelope please..... Based on a completely unscientific, unsubstantiated, nonbinding, and otherwise meaningless poll of a small number of geeks willing to vote on such things --- the winners of the Top Pharmacoinformatic articles of 2008 are (drum roll please):


Workarounds to Barcode Medication Administration Systems: Their Occurrences, Causes, and Threats to Patient Safety doi:10.1197/jamia.M2616


Effectiveness of a Barcode Medication Administration System in Reducing Preventable Adverse Drug Events in a Neonatal Intensive Care Unit: A Prospective Cohort Study doi:10.1016/j.jpeds.2008.08.025


Severity of medication administration errors detected by a bar-code medication administration system American Journal of Health-System Pharmacy, Vol. 65, Issue 17, 1661-1666


The (Slowly) Vanishing Prescription Pad NEJM Volume 359:115-117 July 10, 2008 Number 2


Saving Lives, Saving Money: The Imperative for Computerized Physician Order Entry in Massachusetts Hospitals: Released Feb. 14, 2008 http://www.masstech.org/ehealth/cpoe/cpoe08release.html


Opportunities for Enhancing the FDA Guidance on Pharmacovigilance JAMA. 2008;300(8):952-954 (doi:10.1001/jama.300.8.952)


Drug target identification using side-effect similarity. Science 11 July 2008 http://www.sciencemag.org/cgi/content/abstract/321/5886/263


UCSF Program Achieves over 56% Reduction in Medication Administration Error http://findarticles.com/p/articles/mi_m0EIN/is_2008_March_26/ai_n24959258/print?tag=artBody;col1


Improving antibiotic prescribing for adults with community acquired pneumonia: Does a computerised decision support system achieve more than academic detailing alone? http://www.biomedcentral.com/1472-6947/8/35


Pharmacy Informatics Syllabi in Doctor of Pharmacy Programs in the US http://www.ajpe.org/view.asp?art=aj720489&pdf=yes


Comments, critiques, kudos, criticisms or cynicisms are welcome and encouraged!